Anxiety and Pain Relief Gummy
Key Active Ingredients:
1. Proprietary Anxiety and Pain Relief Blend:
- CBD (Broad-Spectrum)
- GABA (Gamma-Aminobutyric Acid)
- Lemon Balm Extract
2. Proprietary Gummy Base:
- non-GMO, Organic Cane Sugar
- Naturally Derived Tapioca
- Naturally Derived Pectin
- Pure Triple Filtered Water
- Natural Flavors and Colors
Evidence-Based Research and Highlights:
- Proprietary Anxiety and Pain Relief Blend:
- 1. L-Theanine:
- Binds to Glutamate receptors and ionotropic glutamate receptors (AMPA, and NMDA) increasing Dopamine and Serotonin levels in the brain. 
- Increases alpha wave activity in the brain.
- Natural amino acid derivative from green tea.
- Has multiple human clinical trials showing effectiveness at reducing stress levels in the body and promoting healthy relaxation. ,,
- Reduces several stress chemicals in the body that attribute to both physical and mental stress. ,,
- Promotes mental clarity and overall cognition. ,,
- 2. CBD (Broad-Spectrum)
- Interacts with several receptors in the body that regulate anxiety and stress-related behaviors, including the Cannabinoid Type I Receptor (CB1R), the Serotonin 5-HT1a Receptor and the Vanilloid Type I Receptor (TRPV1). ,
- Has been shown to reduce the symptoms and severity associated with anxiety without promoting any psychotropic or euphoric affects associated with THC. ,,,,,,
- Promotes healthy sleep and relaxation. 
- Boosts endogenous (made inside the body) levels of Endocannabinoids by inhibiting their breakdown. ,,
- Inhibits the reuptake of GABA and several other chemicals that promote a feeling of wellbeing and relaxation. ,
- Binds to several opioid and dopamine receptors throughout the body, helping mitigate both acute and chronic pain. ,
- Helps reduce inflammation associated with pain. ,
3. GABA (Gamma-Aminobutyric Acid)
- Gamma-aminobutyric Acid is an inhibitory neurotransmitter made in the human body and is found in several edible plants naturally.
- GABA binds to its receptors found primarily in the brain and enteric (gastrointestinal) nervous systems causing reduced neuroexcitation or reduced stress and anxiety. ,
- Has been shown to improve onset and maintenance of sleep as well as overall sleep satisfaction. ,
4. Lemon Balm Extract :
- Contains several active phytochemicals, including Hydroxycinnamic Acid.
- Has been shown to significantly improve overall anxiety and depression scores in humans. ,,
- Ameliorates anxiety-associated symptoms and improves insomnia. ,,
- Enhances cognitive performance and improves overall mood. 
- Proprietary Gummy Base:
- Contains NO artificial colors, flavors, sweeteners or fillers.
- Organic, Non-GMO Cane Sugar.
- All Natural (plant-based and sustainable) Pectin and Tapioca.
- Pure, Triple-Filtered Water.
- 100% Vegan.
- Manufactured in a cGMP and FDA Registered Facility in the United States.
- Physician Formulated.
- Giesbrecht T, Rycroft JA, Rowson MJ, De Bruin EA. The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutr Neurosci . 2010;13(6):283-290.
- Einöther SJ, Martens VE, Rycroft JA, De Bruin EA. L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness. Appetite . 2010;54(2):406-409.
- Owen GN, Parnell H, De Bruin EA, Rycroft JA. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci . 2008;11(4):193-198.
- Park SK, Jung IC, Lee WK, et al. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J Med Food . 2011;14(4):334-343.
- Haskell CF, Kennedy DO, Milne AL, Wesnes KA, Scholey AB. The effects of L-theanine, caffeine, and their combination on cognition and mood. Biol Psychol . 2008;77(2):113-122.
- Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol . 2007;74(1):39-45.
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