Anxiety and Pain Relief Gummy


Key Active Ingredients:

1. Proprietary Anxiety and Pain Relief Blend:

    • L-Theanine
    • CBD (Broad-Spectrum)
    • GABA (Gamma-Aminobutyric Acid)
    • Lemon Balm Extract

2. Proprietary Gummy Base:

    • non-GMO, Organic Cane Sugar
    • Naturally Derived Tapioca
    • Naturally Derived Pectin
    • Pure Triple Filtered Water
    • Natural Flavors and Colors

Evidence-Based Research and Highlights:

  • Proprietary Anxiety and Pain Relief Blend:
    1. L-Theanine:
      • Binds to Glutamate receptors and ionotropic glutamate receptors (AMPA, and NMDA) increasing Dopamine and Serotonin levels in the brain. [3]
      • Increases alpha wave activity in the brain.
      • Natural amino acid derivative from green tea.
      • Has multiple human clinical trials showing effectiveness at reducing stress levels in the body and promoting healthy relaxation. [3],[5],[6]
      • Reduces several stress chemicals in the body that attribute to both physical and mental stress. [3],[5],[6]
      • Promotes mental clarity and overall cognition. [1],[2],[5]
    2. CBD (Broad-Spectrum)
      • Interacts with several receptors in the body that regulate anxiety and stress-related behaviors, including the Cannabinoid Type I Receptor (CB1R), the Serotonin 5-HT1a Receptor and the Vanilloid Type I Receptor (TRPV1). [7],[13]
      • Has been shown to reduce the symptoms and severity associated with anxiety without promoting any psychotropic or euphoric affects associated with THC. [7],[8],[9],[10],[11],[12],[15]
      • Promotes healthy sleep and relaxation. [9]
      • Boosts endogenous (made inside the body) levels of Endocannabinoids by inhibiting their breakdown. [10],[12],[13]
      • Inhibits the reuptake of GABA and several other chemicals that promote a feeling of wellbeing and relaxation. [13],[15]
      • Binds to several opioid and dopamine receptors throughout the body, helping mitigate both acute and chronic pain. [14],[16]
      • Helps reduce inflammation associated with pain. [14],[16]
3. GABA (Gamma-Aminobutyric Acid)
      • Gamma-aminobutyric Acid is an inhibitory neurotransmitter made in the human body and is found in several edible plants naturally.
      • GABA binds to its receptors found primarily in the brain and enteric (gastrointestinal) nervous systems causing reduced neuroexcitation or reduced stress and anxiety. [17],[19]
      • Has been shown to improve onset and maintenance of sleep as well as overall sleep satisfaction. [17],[19]
4. Lemon Balm Extract :
      • Contains several active phytochemicals, including Hydroxycinnamic Acid.
      • Has been shown to significantly improve overall anxiety and depression scores in humans. [18],[20],[21]
      • Ameliorates anxiety-associated symptoms and improves insomnia. [18],[20],[21]
      • Enhances cognitive performance and improves overall mood. [21]
  • Proprietary Gummy Base:
      • Contains NO artificial colors, flavors, sweeteners or fillers.
      • Organic, Non-GMO Cane Sugar.
      • All Natural (plant-based and sustainable) Pectin and Tapioca.
      • Pure, Triple-Filtered Water.
      • 100% Vegan.
      • Gluten-Free
      • Manufactured in a cGMP and FDA Registered Facility in the United States.
      • Physician Formulated.




  1. Giesbrecht T, Rycroft JA, Rowson MJ, De Bruin EA. The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutr Neurosci . 2010;13(6):283-290. 
  2. Einöther SJ, Martens VE, Rycroft JA, De Bruin EA. L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness. Appetite . 2010;54(2):406-409. 
  3. Owen GN, Parnell H, De Bruin EA, Rycroft JA. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci . 2008;11(4):193-198.
  4. Park SK, Jung IC, Lee WK, et al. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J Med Food . 2011;14(4):334-343.
  5. Haskell CF, Kennedy DO, Milne AL, Wesnes KA, Scholey AB. The effects of L-theanine, caffeine, and their combination on cognition and mood. Biol Psychol . 2008;77(2):113-122. 
  6. Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol . 2007;74(1):39-45.
  7. Skelley JW, et al. “Use of cannabidiol in anxiety and anxiety-related disorders.” Journal of American Pharmacology Association. Jan-Feb 2020; 60(1): 253-261.
  8. Blessing EM, et al. “Cannabidiol as a potential treatment for anxiety disorders.” Neurotherapeutics. 2015 Oct; 12(4): 825-36.
  9. Shannon S, et al. “Cannabidiol in anxiety and sleep: a large case series.” The Permanente Journal. 2019; 23: 18-041.
  10. Melas PA, et al. “Cannabidiol as a potential treatment for anxiety and mood disorders: molecular targets and epigenetic insights from preclinical research.” Int Journal of Molecular Sciences. 2021 Feb 13; 22(4): 1863.
  11. Larsen C, et al. “Dosage, efficacy and safety of cannabidiol administration in adults: a systematic review of human trials.” Journal of Clinical Med Res. 2020 Mar; 12(3): 129-141.
  12. Wright M, et al. “Use of cannabidiol for the treatment of anxiety: a short synthesis of pre-clinical and clinical evidence.” Cannabis Cannabinoid Res. 2020 Sep 2; 5(3): 191-196.
  13. Mlost J, et al. “Cannabidiol for pain treatment: focus on pharmacology and mechanism of action.” Int Journal of Molecular Sciences. 2020 Nov; 21(22): 8870.
  14. Gusho CA, et al. “Cannabidiol: a brief review of its therapeutic and pharmacologic efficacy in the management of joint disease.” Cureus. 2020 Mar; 12(3): 7375.
  15. Black N, et al. “Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis.” The Lancet. Psychiatry. 2019 Dec. 6(12): 995-1010.
  16. VanDolah HJ, et al. “Clinicians’ guide to cannabidiol and hemp oils.” Mayo Clinical Proceedings. 2019 Sep. 94(9): 1840-1851.
  17. Hepsomali P, et al. “Effects of oral gamma-aminobutyric acid administration on stress and sleep in humans: a systematic review.” Frontiers in Neuroscience. 2020; 14: 923.
  18. Savage K, et al. “GABA-modulating phytomedicines for anxiety: a systematic review of preclinical and clinical evidence.” Phytother Res. 2018 Jan; 32(1): 3-18.
  19. Boonstra E, et al. “Neurotransmitters as food supplements: the effects of GABA on brain and behavior.” Frontiers of Psychology. 2015; 6: 1520.
  20. Ghazizadeh J, et al. “The effects of lemon balm on depression and anxiety in clinical trials: a systematic review and meta-analysis.” Phytother Res. 2021 Dec; 35(12): 6690-6705.
  21. Cases J, et al. “Pilot trial of Melissa officinalis extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances.” Med Journal of Nutrition and Metabolism. 2011; 4(3): 211-218.